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所在位置:所有产品 > 抗体抗原 > 一抗 > SMC1A抗体
SMC1A抗体图片
产品货号:
Z34052
中文名称:
SMC1A抗体
英文名称:
Anti-SMC1A Antibody (Clone#5B6)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-SMC1A Antibody (Clone#5B6)
指标别名CDLS2;DXS423E;KIAA0178;SB1.8;SMC 1 alpha;SMC 1A;SMC protein 1A;SMC1;SMC1A;SMC1alpha;SMC1L1;SMCB
克隆性Monoclonal
检验物种human
应用范围WB,IHC,IF,FCM
基因名称SMC1A
克隆号5B6
抗体来源Mouse
免疫原Purified recombinant fragment of human SMC1 expressed in E.Coli.
计算分子量143KD
成分Ascitic fluid containing 0.03% sodium azide.
纯化方式Ascitic fluid
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料Structural maintenance of chromosomes protein 1A (SMC1A) is a protein that in humans is encoded by the SMC1A gene.Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins,SMC3 and either SMC1B or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis,although those complexes at the kinetochore remain.Therefore,the encoded protein is thought to be an important part of functional kinetochores.In addition,this protein interacts with BRCA1 and is phosphorylated by ATM,indicating a potential role for this protein in DNA repair.This gene,which belongs to the SMC gene family,is located in an area of the X-chromosome that escapes X inactivation.Mutations in this gene result in Cornelia de Lange syndrome.Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot IDQ14683
基因名全称Structural maintenance of chromosomes protein 1A
推荐稀释比WB,1:500~1:2000
IHC,1:200~1:1000
IF,1:200~1:1000
FC,1:200~1:400

相关搜索:SMC1A抗体SMC1A单抗Anti-SMC1A Antibody (Clone#5B6)
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