
产品货号:
Z34052
中文名称:
SMC1A抗体
英文名称:
Anti-SMC1A Antibody (Clone#5B6)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SMC1A Antibody (Clone#5B6) |
指标别名 | CDLS2;DXS423E;KIAA0178;SB1.8;SMC 1 alpha;SMC 1A;SMC protein 1A;SMC1;SMC1A;SMC1alpha;SMC1L1;SMCB |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,IF,FCM |
基因名称 | SMC1A |
克隆号 | 5B6 |
抗体来源 | Mouse |
免疫原 | Purified recombinant fragment of human SMC1 expressed in E.Coli. |
计算分子量 | 143KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Ascitic fluid |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Structural maintenance of chromosomes protein 1A (SMC1A) is a protein that in humans is encoded by the SMC1A gene.Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins,SMC3 and either SMC1B or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis,although those complexes at the kinetochore remain.Therefore,the encoded protein is thought to be an important part of functional kinetochores.In addition,this protein interacts with BRCA1 and is phosphorylated by ATM,indicating a potential role for this protein in DNA repair.This gene,which belongs to the SMC gene family,is located in an area of the X-chromosome that escapes X inactivation.Mutations in this gene result in Cornelia de Lange syndrome.Alternative splicing results in multiple transcript variants encoding different isoforms. |
Uniprot ID | Q14683 |
基因名全称 | Structural maintenance of chromosomes protein 1A |
推荐稀释比 | WB,1:500~1:2000 IHC,1:200~1:1000 IF,1:200~1:1000 FC,1:200~1:400 |
相关搜索:SMC1A抗体,SMC1A单抗,Anti-SMC1A Antibody (Clone#5B6)